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Saturday, April 21, 2018

Johns Hopkins researchers invent new class of immunotherapy drugs to fight cancer

Johns Hopkins researchers have invented a new class of cancer immunotherapy drugs that are more effective at harnessing the power of the immune system to fight cancer. This new approach, which was reported in Nature Communications, results in a significant decrease of tumor growth, even against cancers that do not respond to existing immunotherapy.
"The immune system is naturally able to detect and eliminate tumor cells. However, virtually all cancers -; including the most common cancers, from lung, breast and colon cancers to melanomas and lymphomas -; evolve to counteract and defeat such immune surveillance by co-opting and amplifying natural mechanisms of immune suppression," says Atul Bedi, M.D., M.B.A., an associate professor of otolaryngology -; head and neck surgery at the Johns Hopkins University School of Medicine, and senior author of the study.
Major way tumors evade the immune system is via regulatory T cells (Tregs), a subset of immune cells that turn off the immune system's ability to attack tumor cells. Tumors are frequently infiltrated by Tregs, and this is strongly correlated with poor outcome in multiple cancer types.
Many tumors produce high levels of a protein that promotes the development of Tregs. Bedi's team reasoned that since Tregs in the tumor shut down immune responses against tumor cells, turning off Tregs may help immunotherapy work better.
"This is especially challenging because Tregs are not only induced by the TGF-beta (transforming growth factor-beta) protein made by tumor cells but make their own TGF-beta to maintain their identity and function in the tumor," says Bedi. Tregs also make cytotoxic T-lymphocyte associated protein 4 (CTLA-4), which prevents anti-tumor immune cells from acting.
To address this problem, the researchers invented a new class of immunotherapy drugs they called Y-traps. Each Y-trap molecule is an antibody shaped like a Y and fused to a molecular "trap" that captures other molecules nearby, rendering them useless.
The researchers first designed a Y-trap that targets CTLA-4 and traps TGF-beta. This Y-trap disables both CTLA-4 and TGF-beta, which allows anti-tumor immune cells to fight the tumor and turns down Treg cells.
To test the Y-traps, the team transplanted human cancer cells into mice engineered to have human immune cells. The researchers found that their Y-trap eliminated Treg cells in tumors and slowed the growth of tumors that failed to respond to ipilimumab, a current immunotherapy drug that targets the CTLA-4 protein.
"Tregs have long been a thorn in the side of cancer immunotherapy," says Bedi. "We've finally found a way to overcome this hurdle with this CTLA-4-targeted Y-trap."
Antibodies to another immune checkpoint protein, PD-1, or its ligand (PD-L1), are a central focus of current cancer immunotherapy. While they work in some patients, they don't work in the vast majority of patients.
The research team designed a Y-trap targeting PD-L1 and trapping TGF-beta. Tested against the same engineered mice, they found that their Y-trap works better than just PD-L1-targeting drugs atezolizumab and avelumab. Again, this Y-trap slowed the growth of tumors that previously had not responded to drugs.
"These first-in-class Y-traps are just the beginning. We have already invented a whole family of these multifunctional molecules based on the Y-trap technology. Since mechanisms of immune dysfunction are shared across many types of cancer, this approach could have broad impact on improving cancer immunotherapy," says Bedi. "Y-traps could also provide a therapeutic strategy against tumors that resist current immune checkpoint inhibitors."
"This approach appears to be an innovative strategy, and an exciting technical accomplishment to target multiple suppressive mechanisms in the tumor microenvironment," says Robert Ferris, M.D., Ph.D., professor of oncology and director of the Hillman Cancer Center at the University of Pittsburgh. Ferris was not connected with the study. "I look forward to seeing its translation into the clinic."
Bedi envisions using Y-traps not only for treatment of advanced, metastatic cancers but also as a neoadjuvant therapy to create a "vaccine" effect -; that is, giving them to patients before surgery to prevent recurrence of the disease.

I am 70 Years Old and I Do Not Have a Single Joint Pain; I Will Let You Know My Solution

If you have some time with a knee pain, you have a hard time walking, and you spend a lot of time in bed due to pain. However, today I want to teach you the best natural treatment to fight these terrible pains and to be able to walk again and perform normally in your daily life.
The reality is that this remedy is a shake that you can use both as a drink and as an ointment. The best thing about this is that you can do it yourself from the comfort of your home, with ingredients that you probably have in your fridge.

So if you want to end these terrible joint pain, read to the end and learn to prepare it. Do you want to know more? Keep Reading …

Undoubtedly, joint pain is still a challenge with which traditional medicine has not yet been able to give a concrete and effective response. So far there are only treatments to relieve joint discomfort through anti-inflammatory drugs and that can produce certain effects at the stomach level.
Conditions such as osteoarthritis or arthritis that cause joint pain almost permanently are very difficult to treat. These diseases are leading to a definite and secure immobility, therefore these people are forced to use canes or lie down for a long time.
Due to this, we must mention that there is a very effective Russian remedy in natural medicine that will help you with joint pain, in addition to working to slow down the progression of the disease. That’s why today we will introduce you how to prepare it.
Remedy for joint pain:
Ingredients:
-1 eggplant
-1 liter of water
preparation:
In a pot until it boils. Remove from the heat and place the sliced aubergine inside the hot water.
Let the water cool and when you take room temperature strain the preparation. You must store 750 ml of this mixture on one side and keep the rest in another container.
For internal use:
The 750 ml that you set aside before, you should divide it into three shots throughout the day in the following way: one take on an empty stomach, the second take before lunch and the last before going to sleep.
For external use:
The remaining 250 ml you should add 50 ml of olive oil. Mix well both ingredients and apply on painful areas rubbing gently before going to sleep. It is necessary to keep the affected areas warm, it is best to place a cloth with a bandage to keep it in place.

Saturday, March 31, 2018

Guide to Uterine Cancer



What Is It?

It’s a cancerous tumor in your uterus, the pear-shaped organ also known as your womb. Most women get it in the lining of the uterus (endometrium), but you can get tumors in the muscles there, too. Almost 50,000 women in the U.S. get this type of cancer each year. If you’re past menopause, your chances are higher.
Early Signs
If you haven’t been through menopause and you have bleeding or spotting -- a red, pink, or white discharge -- between periods, see your doctor. The same is true if you’ve been through menopause and have these same symptoms any time. Bleeding can be a sign of uterine cancer, but it’s also a symptom of a few other medical problems. It can be normal for some women. Your doctor can help you figure out what’s going on.

Other Symptoms

Let your doctor know if you have:
  • Pain in your pelvis (the area between your hips)
  • Lost weight without trying
  • Pain during sex
  • A hard time peeing or it hurts to pee
It’s best if you find uterine cancer before it grows or spreads, so don’t put off your checkups or ignore symptoms.

How It’s Diagnosed

You may have an ultrasound so your doctor can see inside your uterus, and she may send a tiny telescope in through your vagina to get a closer look. But a biopsy is the best way to know if it’s cancer: Your doctor will take a small amount of tissue from the lining and look for cancer cells under a microscope.

Has It spread?

If you have uterine cancer, your doctor will start with one or more of the following to see if it’s spread to nearby organs, like your cervix, or to your lymph nodes (tiny glands in your neck, armpits, and groin):
  • Ultrasound
  • MRI scan, which uses powerful magnets and radio waves to make detailed images of parts of your body
  • CT scan, which takes X-rays from different angles and puts them together to make a more complete picture.

Radiation

Your doctor may recommend this after surgery to kill any cancer cells that may still be there. It may also be an option if surgery isn’t a good idea for you. Your doctor will put tiny radioactive seeds near your tumor or beam radiation at your uterus to kill harmful cells. New types of radiation treatment make a 3-dimensional beam that’s the exact shape of the tumor.

Hormone Therapy

Estrogen and other hormones in your body can make uterine cancer grow or spread faster. New drugs like progestins, tamoxifen, LHRH agonists, and aromatase inhibitors block these hormones to slow the tumor’s growth. This can cause side effects that feel like menopause, including hot flashes, weight gain, or dryness in your vagina.

Targeted Therapy

Some newer drugs use your own cells against the tumor. Antibodies are things your body makes to knock out bugs that make you sick. In targeted therapy, your doctor puts antibodies into your blood to find and destroy the cancer cells. These smart bombs also can carry tiny bits of radiation straight to your tumor to help in the attack.

Clinical Trials

You may be able to be part of a test for new and better drugs to treat uterine cancer. Ask your doctor if there are trials in your area and if one might be right for you.

Your Sex Life

Side effects of uterine cancer treatment can change your sex life. Vaginal dryness or mood changes from hormone therapy may make sex painful or curb your desire. If you’ve had surgery to remove both your ovaries and uterus, you may have the same issues. But lubricants can help with dryness, and some women say their sex lives actually get better after surgery because they have less pain and other symptoms.

Pregnancy

While most women who get uterine cancer are past menopause, younger women can get it, too. If you hope to have children, talk to your doctor about your options, such as storing eggs, before you begin treatment -- surgery, radiation, and hormones can affect your fertility. 

Can You Prevent It?

Get regular women’s health checkups so your doctor can spot any signs of cancer early. Your age, genes, and family history may raise your chance of uterine cancer, but you can do some things to help prevent it, like stay at a healthy weight and get plenty of exercises. And if you have diabetes or high blood pressure, work with your doctor to control it.

Scientists Just Discovered A New Human Organ, And It Could Have Huge Implications For How We Treat Cancer


Scientists Just Discovered A New Human Organ, And It Could Have Huge Implications For How We Treat Cancer.


You would think, after thousands of years of study, we’d have nailed down what was going on inside us. But researchers are arguing that they have accidentally discovered an entirely new organ.
The new structure could even help explain where much of the fluid in our body sits, and may even be the source of lymph, the fluid that is essential to the functioning of our immune system. As such this network, or structure, of fluid-filled channels could be playing a significant role in maintaining our health, as well as propagating disease.
It's not even limited to the obscure parts of us – it is found wrapped around many of our other, more well known, organs. You see, while we thought our lungs, digestive tract, and even our skin were surrounded by tough and dense connective tissue, it turns out that this tissue is in fact riddled with spaces supported through a meshwork of strong connective proteins to prevent them from collapsing, and which freely allow fluid to flow.


This could help explain where so much of our body’s fluid goes. While our cells contain most of the fluid, and the circulatory system carries a whole load more, over a third went unaccounted for and was simply said to be “interstitial”, or just floating around between organs and cells. The researchers claim, in a paper published in Scientific Advances, that the “interstitium” should be defined as an organ in its own right.
They think it may explain why some forms of cancer can spread so rapidly and between unrelated organs. It might also help explain why wrinkles develop, as when you age these channels in the tissue under your skin may fold in on themselves.
It was while conducting routine endoscopies of patients that doctors noticed that the tissue surrounding the bile duct, which should have been fairly solid and dense, was actually covered in an intriguing pattern. When one then decided to take a look using the same device under the skin of his nose, he surprisingly found exactly the same effect.
The key, it seems, was looking at living tissue at such fine magnification. Up until now, medical researchers have relied on fixed tissue microscope slides when studying the human body, say the authors. To do this, they take thin slices of tissue, treat it with chemicals, and dye the structures so that they can be easily identified when placed under a microscope.
The problem, however, is that the fixing drains the tissue of all fluid, and it is expected that this process collapses all the once fluid-filled compartments of the interstitium. Because of this, researchers looking at slides of organs have simply assumed the flattened compartments were tears in the tissue.
It now seems that they will need to do more work to define this structure and convince others that it is an organ in its own right, rather than just a new type of tissue.
“This finding has potential to drive dramatic advances in medicine, including the possibility that the direct sampling of interstitial fluid may become a powerful diagnostic tool," explained co-author Neil Theise.

Russian Scientists Discover Protein Which Causes Cancer Cells to Self-Destruct

The unusual protein, found in the skin cells of human beings and other warm-blooded animals, has a molecular structure similar to that of the toxins of snakes and other reptiles.

Molecular biologists from Moscow State University and the Russian Academy of Sciences have discovered proteins that can help suppress the growth of cancerous tumors. 
The genomes of human beings and other multicellular organisms contain several sets of genes with special 'instructions', calling on their cells to self-destruct when certain conditions are met. Usually, these reactions are triggered not as a result of internal cellular processes, but through contact of cell membranes with specific signal-sending molecules. This allows the immune system to kill 'rebellious' cells which threaten to cause cancerous tumors and clear the organism of weak and old cells.
Dr. Mikhail Shulepko of the Russian Academy of Sciences' Institute of Biochemistry, coauthor of a new study on the subject, explained that special proteins in mammalian skin cells have been found to have a structure similar to that of toxins of snakes and other reptiles. However, unlike their toxic 'cousins', which work to block the transmission of nerve impulses, the mammalian proteins, called SLURPs, act not on the nervous system, but on all cells in general, and speed up or slow down their growth.
The scientists' find prompted them to consider whether such proteins could be used to fight against cancer as a kind of 'stop signal' against the proliferation of cancer cells. They tested this idea by growing skin, breast, lung and rectum cells in a lab and treating them with large quantities of the SLURP-1 and SLURP-2 proteins.
Their research, published in the British Journal of Pharmacology, showed that both proteins significantly slowed the growth of nearly all types of cancer, blocking the work of special receptors on the surface of cells which cause them to divide. The biologists found that after a day of such treatment, the number of cancer cells dropped by 40-70% compared to tumor control samples.
Furthermore, the injection of large quantities of SLURP-1 and SLURP-2 proteins into the cellular nutrient medium caused cancerous cells to produce even more of these same molecules, leading to a chain reaction and resulting in the cancer cells to essentially destroy themselves.
"We will continue to study how SLURP works on other cancer models, including cell cultures of primary tumors, as well as human tumors implanted on the bodies of laboratory animals. If these effects are confirmed, it will be possible to consider clinical studies for our proteins," Dr. Shulepko said.
According to the biologists, more work is still required to determine how exactly these proteins cause cancer cells to self-destruct, and what role they play in the work of the body.

Friday, March 16, 2018

Statins are gateway drugs for Big Pharma: Take one and you’ll need four or five more prescriptions for the side effects



One out of every three American adults take statins, and if you think that sounds like good news for statin manufacturers, you’re missing the bigger picture. All of Big Pharmabenefits when people take statins. In fact, statins can really be thought of as gateway drugs. After all, they have so many side effects that you will likely end up taking several other medications after you start statins just to deal with them.
What can happen to you if you take these dangerous drugs? They suppress your body’s immune system, rendering it less able to fight off infections. They also inhibit production of coenzyme Q10, which helps to regulate your immune and nervous system and maintain a healthy heart and blood pressure. There’s also a higher risk of neurological diseases when you take statins, with many patients reporting forgetfulness, confusion and memory loss. But don’t worry – whatever happens to you, Big Pharma has a solution for that, too!

Highly increase risk of diabetes

Statins also increase your risk of diabetes, so much so that the FDA has required that a warning label be placed on the package informing people of the link between statins, higher blood glucose levels and diabetes. The risk is especially heightened if you are an older woman. An Australian study found that elderly women who took high doses of statins had a 50 percent higher risk of developing diabetes. This could mean you’ll end up on diabetes medication for the rest of your life.
And for what benefit are you placing yourself at so much risk? According to research published in BMJ, taking statins over the course of two to five years adds just 3.2 days to a patient’s lifespan on average – if the side effects don’t kill them first. Yes, they’ve been approved by the FDA, but how many times has the FDA had to pull drugs after initially approving them as their dangers became too obvious to ignore?

Statin alternatives

If all this make you want to keep your distance from statins, you will be pleased to know there are some great alternatives. Dr. Jack Wolfson, a Phoenix-area holistic cardiologist, believes that a wellness model needs to be followed rather than a sickness one.
In an interview with Mike Adams, the Health Ranger, he pointed out that cardiologists sometimes fall into the easy routine of blindly prescribing statins as Big Pharma tells them to and collecting a paycheck. After all, they’ve got medical school loans to pay off.
Dr. Wolfson asks why people would want to choose statins, which can reduce the risks associated with high cholesterol slightly yet put them at risk of many other problems, when they could take safe actions that bring their risks down to zero? He said that nobody says they feel better when they take statins and blood pressure medications. In contrast, those who turn to evidence-based supplements often report feeling great, losing weight, and having more energy.

Natural alternatives

Some of the alternatives he mentioned in the interview include beetroot powder, magnesium, and Omega 3. He says that we can make such a big difference in our health through food., and he also points out how powerful the sun can be in keeping us healthy. He also suggests that people get more physical activity, such as walking or gardening.
When your health is less than optimum, Dr. Wolfson says, your body is deficient in nutrients, not pharmaceuticals. Drugs might be good for emergencies, but when it comes to prevention, you can’t beat a healthy, well-rounded and nutritious diet, physical activity, and good old-fashioned sunshine. What do you have to lose by trying it?

Newly Engineered Antibody Can Fight Back Against 99 Percent of HIV Strains

A new study has produced an antibody that's able to kill off 99 percent of HIV strains. The protein is made up of three broadly neutralizing antibodies, and it is said to be more effective than any naturally occurring antibody that's been discovered.

ADVANCED ANTIBODIES

Research carried out by the U.S. National Institutes of Health (NIH) in conjunction with pharmaceutical firm Sanofi has produced an antibody capable of attacking 99 percent of HIV strains. The International Aids Society has heralded the finding as an “exciting breakthrough.”
The human body has difficulty fighting HIV because of the way that the virus changes and mutates — a single patient can have numerous unique strains of the infection present in their body simultaneously. However, a slim minority of people who suffer from HIV eventually develop a means of battling back in the form of broadly neutralizing antibodies.
These proteins are capable of killing off numerous HIV strains at once, so for this joint study between NIH and Sanofi, researchers set out to find a way to harness this natural defense.


To that end, they combined three unique antibodies to produce a tri-specific antibody. While the most effective naturally occurring antibodies can only target 90 percent of HIV strains, this tri-specific antibody was observed to take on 99 percent. It was even successful at low concentrations. Furthermore, an experiment in which 24 monkeys were administered with the antibodies and then injected with the virus didn’t result in a single infection.
As Sanofi’s Dr. Gary Nabel told the BBC, “[The tri-specific antibodies] are more potent and have greater breadth than any single naturally occurring antibody that’s been discovered.” The next step to putting these powerful antibodies to work is a clinical trial, which is expected to get underway in 2018.

STILL MUCH TO DO

Over the last few decades, we have seen some amazing advances in the fight against HIV. These range from the various treatment methods that are now available to the hugely successful educational campaign that’s been carried out in Africa.

Truly, no stone is being left unturned in the search for better HIV treatments. Scientists in South Africa are investigating the case of a nine-year-old child who was seemingly cured of HIV after receiving antiretroviral therapy. Another study saw researchers look into cows’ ability to produce broadly neutralizing antibodies with the goal of using them to combat the virus.
With any luck, methodology will continue to improve at a fast pace. At the end of 2015, 36.7 million people around the world were living with HIV/AIDS, so clearly a lot more work needs to be done. However, this new research project and others like it could lead to the next level of advancements with regards to the virus.


12 Health Benefits Of Okra That Will Make You Love Greens



A good filler food, okra not only curbs hunger but keeps you from tiring, too. It also strengthens your immunity against conditions like diabetes, high cholesterol, Alzheimer’s, liver disease, breast cancer, and asthma. Being rich in vitamins A, C, and K, it helps fortify bones while also improving your eyesight. Experiment with okra water, peels, and powdered seeds to see what suits you best.

Health Benefits Of Okra


Ethiopian in origin, Abelmoschus esculentus or Hibiscus esculentus is known by many names around the world – okra, okro, lady’s finger (England), gumbo (U.S.), guino-gombo (Spain), guibeiro (Portugal), Kacang bendi (Malaysia), and bhindi, gombo, and bendakai (India). The fact that it even has that many names suggests its global popularity and widespread cultivation. The tender, young, seed-containing pod of the okra plant is eaten as a vegetable in salads, broths, stews, and stir-fries.
Being a green veggie, it is easy to wrap your head around the fact that okra is “all healthy.” Here’s what it offers:1 2
Interesting Facts About Okra
  • Cleopatra of Egypt and Yang Guifei of China loved to eat okra.
  • Okra seeds were used as coffee bean substitutes during World War II.
  • Okra found its way to different parts of the world during the Atlantic slave trade.
Nutrients In 1 Cup Of Okra% of Daily Value
Energy33 Calories –
Fiber3.2 gm12.8
Protein1.9 gm –
Carbohydrate7.5 gm –
Fat0.2 gm
Magnesium57 mg14.3
Calcium82 mg8.2
Potassium299 mg8.5
Sodium7 mg –
Vitamin C23 mg38.3
Vitamin K31.3 mg39.1
Folate (vitamin B9)60 µg15
Vitamin A716 IU14.3
Thiamin (vitamin B1)0.2 mg13.3
Vitamin B60.2 mg10.8

Benefits Of Okra

Like a number of natural ingredients, scientists are turning a keen eye to this time-tested home remedy. We now have research to back the folklore – which happened to be right. The following are benefits of okra, most of which would probably have never occurred to us.

1. Packs A Truckload Of Nutrients

Okra pods are loaded with significant amounts of vital nutrients – protein, fiber, calcium, iron, and zinc.3 It, thus, qualifies as an effective economical tool capable of treating malnutrition around the world.

2. Helps Control Hunger

Okra is loaded with soluble fibers.4 Soluble fiber makes you feel full faster and for longer. This can help keep your calorie intake in check, helping you with your weight loss goals. With a longer-lasting feeling of satiety, your need to binge will be curbed immensely.

3. Keeps You From Getting Tired

It is unfortunate how common the word “fatigue” has become in today’s world. What used to be mostly age and sickness-related, is now an everyday struggle for young, healthy individuals. Okra seeds can delay fatiguing.5 They contain antioxidant polyphenols and flavonoids that promote glycogen storage in the liver. Glycogen is a body fuel reserve, and more of it means you will take longer to tire.
This is why okra is also good for individuals suffering from depression. You will be able to fight the feeling of being inexplicably tired.6

4. Manages Diabetes Mellitus

Turkish people have long been consuming an infusion of roasted okra seeds to manage diabetes mellitus.
Okra’s peel and seed can lower blood glucose levels, making them useful in managing diabetes mellitus.7 They do so by inhibiting carb-breaking enzymes, increasing sensitivity to insulin, and ensuring there are sufficient insulin-producing cells in the pancreas.8 More insulin and less breakdown of carbs to glucose means lower blood sugar.
One study proved that okra seeds prevent the intestinal breakdown of carbohydrates to glucose by inhibiting the enzyme alpha-glucosidase.9

5. Stabilizes Cholesterol Levels

Okra would make a great functional food ingredient!
The more finely ground okra powder is, the better it can adsorb cholesterol.10
Okra promotes cholesterol degradation and inhibits the production of fat in the body.11 It, thus, decreases total cholesterol and triglyceride and enhances excretion of bile acids (made from cholesterol) in the feces.
By regulating cholesterol levels in the blood, okra can prevent clogging of arteries – protecting us from heart diseases like atherosclerosis.

6. Fortifies Bones And Prevents Excessive Bleeding

The most abundant vitamin in okra is vitamin K.12 This vitamin helps strengthen bones and promotes clotting of blood. Okra, thus, helps prevent osteoporosis, fractures, and excessive bleeding (due to injury or bleeding disorders).

7. Boosts Immunity And Improves Eyesight

Okra contains moderate levels of vitamin A.13 Vitamin A encourages the production of white blood cells, key players in your immune system. While infections and diseases do their rounds in the general population, okra will equip your body well enough to resist.
Vitamin A also supports eyes health. If you have weak eyesight or if you come from a family with a history of weak eyesight, it makes sense for you to consume okra regularly.

8. Prevents Gastritis

In Asian medicine, the fruit of the okra plant is used as a mucilaginous food additive to treat gastric irritations.
H. pylori bacteria infect the stomach lining and cause inflammation called gastritis. Okra juice contains anti-adhesive compounds that bind to the surface of free-floating bacteria in the gut.14 15 This unanticipated binding blocks sites on the bacteria responsible for docking to the stomach lining. In effect, okra juice prevents H. Pylori infections and gastritis.
A concern that arises is whether okra’s non-specific binding to bacteria can deter normal gut bacteria. Further studies are required to assess whether okra’s benefits outweigh its potential side effects. Having said that, we can take refuge in the fact that okra is eaten widely in Asia and Africa for centuries now with no adverse effects on the digestive system.
Children between 2 to 5 are more vulnerable to H. Pylori infections, so it makes sense to ensure they eat okra regularly.

9. Prevents Liver Disease

Your liver is your body’s prime detox organ. Okra can help ensure it is protected from disease. In one study, chemically-induced liver disease in rats was efficiently counteracted by okra.16 Oral pre-administration of okra extracts reduced the effects of damaging free radicals that cause liver disease. Okra may have done so by stabilizing liver cell membranes, making them more defensive against intruding free radicals.

10. Staves Off Neurodegenerative Disorders

Okra may help reduce the risks of Alzheimer’s in individuals who are genetically predisposed to it.17 It may also help prevent other neurodegenerative diseases related to oxidative stress.
Imagining how difficult it can be to live with a nerve disorder, this benefit of okra is of great preventive value.

11. Kills Breast Cancer Cells

In one study, a lectin isolated from okra was capable of instigating cell suicide in breast cancer cells.18 The growth of breast tumor cells was inhibited by a significant 63%.
Breast cancer affects 1 in 8 women during their lifetime.19 Incorporating okra in your diet may help reduce this statistic drastically.

12. Keeps Asthma Symptoms In Check

Okra seems to be beneficial for asthma patients.20 21 How exactly it does so is not yet known. Some postulate that okra’s high vitamin C content is responsible for its respiratory benefits, however, no clear correlation between vitamin C and asthma exists.22

How To Consume Okra

Cooking Tip: To make okra more palatable, cook it in slightly salted water to reduce its slimy texture.
It is safe to say that for the general population, okra is an acquired taste. You may incorporate it in your meals with some palate-appealing, healthy recipes. To maximize benefits, you may consume the following:

1. Okra Water

Soak okra pods in a glassful of water overnight at room temperature. Some of its water-soluble nutrients and compounds will get leached out into the water. Strain out the pod, and drink the infused water.
Alternatively, you may soak sliced pods instead of whole pods. Bear in mind that there will be a bitter after-taste.

2. Okra Peel

Using a handheld grater or lemon zester, scrape the peel from the okra pod. Directly consume about half a teaspoon of the peel at a time. This is a good way to avoid ingesting okra’s mucilaginous secretion.

3. Okra Powdered Seeds

It is difficult to manually separate okra seeds from the pod and then make a powder. A more pragmatic approach is to buy readily available dried okra seed powder. It is generally advised not to have more than 5 gm of this powder in a day. Check the dosage with your health practitioner, especially if you are on diabetic medications.
An Interesting Fact
In addition to the vast array of nutrients, okra also contains antinutrients that reduce the body’s ability to absorb essential nutrients. However, the antinutrients are low in concentration and the minerals okra offers can easily be absorbed and used by the body (mineral bioavailability is high) despite them.
One can argue that most of the laboratory studies supporting the claims mentioned above use extracts and isolated compounds from okra and not the whole pod. While that is mostly true, natural remedies are best self-tested. They have been proved worthy and effective for centuries now as opposed to antibiotics and drugs developed only in the last century or two. Don’t miss out!
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Disclaimer: The content is purely informative and educational in nature and should not be construed as medical advice. Please use the content only in consultation with an appropriate certified medical or healthcare professional.